Fatty Liver Disease: A Crosstalk Between Lipid Species

Fatty Liver Disease: A Crosstalk Between Lipid Species

Blog Article

The role of different lipid species such as free fatty acids and sphingolipids in non-alcoholic fatty liver disease 3m SMA (NAFLD) has been extensively studied during the last decade.In addition, free cholesterol accumulation in hepatocytes plays a crucial role in the transition from steatosis to steatohepatitis.However, the contribution Bike Units - Comfort - Step-Over of these lipids to NAFLD pathology is often evaluated individually.

This review attempts to enclose the main metabolic and signalling connections between lipotoxic lipid species, and how their homeostasis is disrupted in NAFLD.